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NitroMed, Inc. (NitroMed) believes that addressing concerns about online privacy is critical. NitroMed promises to protect the personal information given to us by visitors to this Web site and information included on our electronic mail lists. Any information that you give to NitroMed will be held with care, and will not be used in ways that you have not consented to. A more detailed explanation about how we care for your personal information follows.

COLLECTION AND USE OF INFORMATION:

Personally Identifiable Information ("Personal Information") is information that can be used to identify or contact you, such as your name, e-mail address, telephone number or similar information. NitroMed only collects Personal Information that you choose to share with us, such as when (1) contacting us via the Site (by clicking on the "Contact Us" button at the top of each Web page), (2) submitting your e-mail address to receive recent news, (3) registering online for an event or course, or (4) upon registration for access to those areas of our Site intended only for licensed medical professionals.

REGISTERED USERS:

If you are a licensed medical professional, to register, you must provide us with certain Personal Information, including your name, profession, e-mail address, postal mail address, title and clinical affiliation. We will use this Personal Information to review and verify your registration information. We may use your Personal Information to send periodic marketing or promotional notices to you or notify you of any changes to this Policy. You can always opt-out of receiving these communications from us by following the "opt out" procedures described below.

Visitors to the BiDil.com Web site are invited to sign up to receive news, event notification, and other information that may be of interest to them. To do this, visitors are asked to provide certain contact information. We do not sell, rent, loan, trade, or lease the personal information on our list to anyone. Details on how to unsubscribe from our e-mail lists are provided in the text of each e-mail distribution to the subscriber.

BROWSER INFORMATION COLLECTED ON THE WEB SITE:

As with many Web site operators, NitroMed analyzes our Web site logs to constantly improve the value of this Web site to our visitors. This includes page views, unique views, unique visitors, repeat visitors, frequency of visits, and peak-volume traffic periods. In our use of this information, we do not gather, request, record, require, collect, or track any Internet users' personally identifiable information.

USE OF "COOKIES":

This Web site may use a technology called a "cookie". A cookie is a piece of information that our Webserver sends to your computer (actually to your browser file) when you access a Web site. Then when you come back our site will detect whether you have one of our cookies on your computer. Our cookies help provide additional functionality to the site and help us analyze site usage more accurately. For instance, our site may set a cookie on your browser that keeps you from needing to remember and then enter a password more than once during a visit to the site.

OTHER USES OF YOUR PERSONAL INFORMATION:

In addition to using information about you for the specific purposes set out above, from time to time we may also use your personal information to send you news about our organization and promotional materials about NitroMed initiatives, provided that you have not opted out of receiving such information as described below.

DISCLOSURE OF INFORMATION:

Resale or disclosure of information to third parties: NitroMed does not sell, rent, loan, trade, or lease personal information collected on this Web site or included on our e-mail lists to any third party.

DATA QUALITY AND ACCESS:

NitroMed provides you with the opportunity to know about the information that NitroMed holds about you, together with the ability to correct, amend or delete, as appropriate, any such information that is incomplete or inaccurate. Should you wish to exercise any of these options or should you have any questions or concerns about information that NitroMed has collected in relation to you, please feel free to contact us by sending a message to info@nitromed.com. Specific details on how to unsubscribe from our e-mail lists are provided in the text of each e-mail distribution.

OPT-OUT:

Although most visitors to the Web sites operated by NitroMed indicate that they welcome details of NitroMed initiatives and other NitroMed materials, we acknowledge that individuals should have the right to choose. You will be given the right to opt out of receiving NitroMed information whenever you are asked to provide personal information on this site. If you do not opt out immediately, but later decide that you do not wish to receive future NitroMed communications, you can notify us of this as set out below.

ENFORCEMENT:

If for any reason you believe that NitroMed has not adhered to these privacy principles, please notify us by e-mail at info@nitromed.com, and we will endeavor to review and correct the problem promptly. Please use the words "Privacy Policy" in the Subject line.

EXTERNAL LINKS:

This Web site provides links to various Web sites that NitroMed does not control. When you click on one of these links, you will be transferred out of our Web site and connected to the Web site of the organization or company that you selected. Even if an affiliation exists between our Web site and a third party Web site, we exercise no control over linked sites. Each of these linked sites maintains its own independent privacy and data collection practices and procedures. If you visit a Web site that is linked to our site, you should consult that site's privacy policy before providing any personal information.

CHILDREN'S PRIVACY:

Because we care about the safety and privacy of children online, we comply with the Children's Online Privacy Protection Act of 1998 (COPPA). COPPA and its accompanying FTC regulation establish United States federal law that protects the privacy of children under 13. Our site is not intended to solicit information of any kind from children under 13.

It is possible that due to fraud or deception by others, we may unknowingly receive information pertaining to children under 13. If we are notified of this, once we have verified the information, we will promptly obtain parental consent or otherwise delete the information from our servers. If you want to notify us of our receipt of information in relation to children under 13, please do so by e-mailing us at info@nitromed.com.

INTERNATIONAL INFORMATION TRANSFERS:

Any personally identifiable information that you provide to NitroMed will be collected directly on servers located in the United States and maintained on servers located in the United States or other countries. If you are located outside the United States, this means that any information you provide will be transferred abroad. While NitroMed is committed to providing your information with the highest level of privacy protection, we believe you should know that the general level of protection for personal information in the United States may not be the same as that provided in other countries.

REGISTERED USERS:

Visitors to the Site may use the public areas of the Site for informational purposes and are subject to these Terms. In addition, certain areas of this Site contain information intended only for medical professionals. Accordingly, NitroMed reserves the right to limit access to certain areas of the Site to medical professionals who register and meet the qualifications imposed by us. The resources provided in password-protected areas of this Site are specific to and intended for medical professionals who specialize in the medical specialties that we serve. To register, a medical professional must provide us with certain personal information, including his or her name, profession, e-mail address, postal address, title and clinical affiliation. If you do not qualify, please do not attempt to register with us. Upon our review and acceptance of your registration information, you will be permitted to select your own User ID and password. The information you provide must be accurate and complete. You will be permitted to update your private information via a profile page once you have successfully logged in using a valid User ID and password. We reserve the right to discontinue access to any restricted area of the Site at any time, without notice to you, for any reason. If you are or become a registered user, you are responsible for maintaining the confidentiality of your User ID and password. If you become aware of unauthorized use of your User ID and password, you agree to immediately notify NitroMed. The personal information provided by you is subject to our Privacy Policy, which can be found at www.BiDil.com.

TERMS AND MODIFICATIONS TO PRIVACY POLICY:

By using this Web site, you signify your agreement to the terms of our privacy policy. If you do not agree with these terms, please do not disclose any personal information through this site.

NitroMed may modify this privacy policy at any time at its discretion and modifications are effective upon being posted on this site. You are responsible for reviewing this privacy policy periodically to ensure that you are aware of any changes to it.

CONTACTING NITROMED ON PRIVACY:

If you have any questions or concerns regarding privacy on the NitroMed Web site, please contact the Webmaster at info@nitromed.com.

This policy was last updated on August, 2007.


Information for Patients about BiDil®

BiDil is approved for use in addition to routine heart medicines to treat heart failure in black patients, to extend life, improve heart failure symptoms, and help patients stay out of the hospital longer. There is little experience in patients with heart failure who experience significant symptoms while at rest. Most patients in the clinical study of BiDil received routine heart failure medicines.

Important Safety Information

Tell your doctor about any allergies you have, especially if you're sensitive to nitrates, such as nitroglycerin tablets or isosorbide dinitrate (Sorbitrate® or Isordil®). BiDil has a nitrate component, so you need to let your doctor know.

Tell your doctor if you're taking any erectile dysfunction or pulmonary hypertension drugs, like Viagra®/Revatio™ (sildenafil), Levitra® (vardenafil) or Cialis® (tadalafil). Mixing these with BiDil may cause a sudden drop in blood pressure, fainting, chest pain, or heart attack.

Also tell your doctor if you are taking any medication to decrease blood pressure because when taken with BiDil, blood pressure may become too low.

Drinking alcohol when taking BiDil could make you feel very lightheaded. We recommend that you try to avoid drinking alcohol while taking BiDil.

It is possible you'll get headaches, especially at first. For some patients, Tylenol® (acetaminophen) helps ease the discomfort. Keep your doctor posted on your headache progress and Tylenol use; he or she may want to adjust your dosage.

If you experience dizziness, call your doctor. Please make sure to tell your doctor about any of the signs or symptoms mentioned below or about any unusual events that worry you.

Drinking less fluids than your doctor recommends or losing fluid due to diarrhea, sweating, or vomiting may cause low blood pressure, lightheadedness, or fainting. If fainting occurs, stop taking BiDil and contact your doctor immediately.

Lightheadedness may occur when standing, especially after sitting or lying down.

If you experience any achy and/or swollen joints, unexplained fever for more than a few days, skin rashes, chest pain, prolonged weakness or fatigue (even after a good night's sleep), or any other unexplained signs or symptoms, make sure to tell your doctor as they may be signs of a serious medical condition.

You may also experience rapid heartbeat that could lead to chest pain or aggravate chest pain, or numbness or tingling in the hands or feet.

Sorbitrate is a registered trademark of AstraZeneca LP; Isordil is a registered trademark of Bioavail Corporation; Viagra is a registered trademark and Revatio is a trademark of Pfizer Inc.; Levitra is a registered trademark of Bayer Healthcare, GlaxoSmithKline, and Schering-Plough; Cialis is a registered trademark of Lilly ICOS LLC. Tylenol is a registered trademark of McNeil Pharmaceuticals, a Division of McNeil PPC, Inc.

Please see full Prescribing Information for BiDil.


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